Synthesis of Some Novel Fused Imidazo [2, 1-b] [1, 3] Thiazole and Imidazo [2, 1-b] Thiazolo [5, 4-d] Isoxazole Derivatives
نویسندگان
چکیده
منابع مشابه
SYNTHESIS OF SOME IMIDAZO [ I , 2-b] [l , 2,4] TRIAZINE AND N-ALKYLATED IMIDAZO [l , 2-b] [1 , 2,4]-TRIAZINES
A number of 3-amino-1, 2, 4-triazin-5 (2H)- ones(1) were synthesized and condensed with a-haloketones to give 2,6-disubstituted imidazo [1, 2-b] [1, 2, 4]-triazin-3 (4H)-ones (2). These compounds were reacted further with a - haloketones to yield N-alkylated products (3).
متن کاملsynthesis of some imidazo [ i , 2-b] [l , 2,4] triazine and n-alkylated imidazo [l , 2-b] [1 , 2,4]-triazines
a number of 3-amino-1, 2, 4-triazin-5 (2h)- ones(1) were synthesized and condensed with a-haloketones to give 2,6-disubstituted imidazo [1, 2-b] [1, 2, 4]-triazin-3 (4h)-ones (2). these compounds were reacted further with a - haloketones to yield n-alkylated products (3).
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1,3,4-Thiadiazole skeleton forms an integral part of various medicinal agents and depicts a vast array of biological activities such as antimicrobial, anti-inflammatory, analgesic, antileishmanial, antitumor, anti-tuberculosis, antileptic, antiviral and other activities. 1,3,4-Thiadiazole moiety has many desirable features which makes them pharmaceutically suitable as it can act as “hydrogen bi...
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The synthesis of 6- methyl- 2- phenyl- 7H- oxazolo [3,2-b] 1,2,4-Triazine- 7-one (6, R=Ph) and its 2-P- bromophenyl analogue to the two members of a new heterocyclic system is described
متن کاملSynthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines
A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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ژورنال
عنوان ژورنال: E-Journal of Chemistry
سال: 2012
ISSN: 0973-4945,2090-9810
DOI: 10.1155/2012/896454